National honey cooperative headquartered in Sioux City. Producer of Sue Bee and Aunt Sue's brand honey products. One of the largest honey cooperatives in the United States.

Open 24/7/365, Siouxland Freedom Park is a 55-acre park located south of South Sioux City, NE, overlooking the Missouri River. The park is home to an exact half-scale replica of the Vietnam Memorial Wall in Washington, D.C. “The Wall” as it’s dubbed, is made from the same granite from India as the wall in D.C. It features the names of 58,272 fallen service members from the Vietnam War.

Regional transit serving Burt, Cedar, Dakota, Dixon, Dodge, Douglas, Madison, Thurston, and Wayne counties in Nebraska, plus Iowa and South Dakota service areas.

Sisco Fertilizer Inc, a fertilizer dealer in Elsie, Nebraska.

Sitz Chiropractic provides chiropractic care and spinal health services for patients in O'Neill, Nebraska and the surrounding Holt County area.