U-Save Pharmacy is an independent pharmacy on West Leota Street near Great Plains Health.

Van Velson Law Office is at 410 East Francis Street, Suite 2 in North Platte.

Waite & McWha Law Firm is at 116 North Dewey Street in North Platte.

Walker Road Church of Christ is a church of Christ congregation located at South Oak Street near Walker Road.

Washington Elementary School is a public elementary school in North Platte Public Schools.

Weathercraft Roofing Company has its North Platte office at 401 E 8th St. It does residential and commercial roofing, including EPDM, TPO, asphalt and metal roofs, along with siding, gutters, windows and overhead doors, and helps with hail damage and insurance claims.

Wendy's is at 1202 South Jeffers Street in North Platte.

The West Central REEC is the University of Nebraska's research farm for the twenty counties of west central Nebraska, at 402 West State Farm Road in North Platte, in Lincoln County. The main site runs about 1,800 acres, roughly 1,100 of it pasture and the rest dryland and irrigated crops, with faculty from eight departments and laboratories for agroecosystem entomology, irrigation water management, pesticide application technology and cropping systems.

Westfield Pharmacy is an independent Health Mart pharmacy in the Westfield Shopping Center.