Full-service regional hospital in downtown Sioux City; formerly MercyOne Siouxland Medical Center, acquired by UnityPoint Health September 2025. 464 licensed beds serving the tri-state Siouxland area. Emergency services, specialty care, trauma center.
Regional hospital serving the tri-state Siouxland area of Iowa, Nebraska, and South Dakota. Comprehensive services including emergency, heart care, cancer care, surgical, and birth center. One of the largest employers in the region.
Multi-specialty physician clinic in Yankton serving southeast South Dakota and northeast Nebraska. Affiliated with Avera Sacred Heart Hospital. More than 40 physicians across primary care and specialty services.
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